Direkt zum Inhalt | Direkt zur Navigation

Benutzerspezifische Werkzeuge

Sie sind hier: Startseite / Forschung / Publikationen



Firner S, Willwacher S, de Marées M, Bleuel J, Zaucke F, Brüggemann GP, Niehoff A (2018). Effect of increased mechanical knee joint loading during running on the serum concentration of cartilage oligomeric matrix protein (COMP). J Orthop Res [Epub ahead of print].

Trost M, Bredow J, Boese CK, Loweg L, Schulte TL, Scaal M, Eysel P, Oppermann J (2018). Biomechanical comparison of fixation with a single screw versus two Kirschner wires in distal chevron osteotomies of the first metatarsal: a cadaver study. J Foot Ankle Surg 57(1):95-99.



Bluhm B, Ehlen HWA, Holzer T, Georgieva VS, Heilig J, Pitzler L, Etich J, Bortecen T, Frie C, Probst K, Niehoff A, Belluoccio D, Van den Bergen J, Brachvogel B (2017). miR-322 stabilizes MEK1 expression to inhibit RAF/MEK/ERK pathway activation in cartilage. Development 144(19):3562-3577.

Dargel J, Boomkamp E, Wegmann K, Eysel P, Müller LP, Hackl M (2017). Reconstruction of the lateral ulnar collateral ligament of the elbow: a comparative biomechanical study. Knee Surg Sports Traumatol Arthrosc 25(3):943-948.

Epro G, Mierau A, Doerner J, Luetkens JA, Scheef L, Kukuk GM, Boecker H, Maganaris CN, Brüggemann GP, Karamanidis K. (2017). The Achilles tendon is mechanosensitive in older adults: adaptations following 14 weeks versus 1.5 years of cyclic strain exercise. J Exp Biol 220(Pt 6):1008-1018.

Firner S, Zaucke F, Michael J, Dargel J, Schiwy-Bochat KH, Heilig J, Rothschild MA, Eysel P, Brüggemann GP, Niehoff A (2017). Extracellular distribution of collagen II and perifibrillar adapter proteins in healthy and osteoarthritic human knee joint cartilage. J Histochem Cytochem 65(10):593-606.

Hackl M, Wegmann K, Kahmann SL, Heinze N, Staat M, Neiss WF, Scaal M, Müller LP4 (2017). Reply to the letter to the editor: shortening osteotomy of the proximal radius. Knee Surg Sports Traumatol Arthrosc 25(10):3328-3329.

Hackl M, Mayer K, Weber M, Staat M, van Riet R, Burkhart KJ, Müller LP, Wegmann K (2017). Plate osteosynthesis of proximal ulna fractures-a biomechanical micromotion analysis. J Hand Surg Am 42(10):834.e1-834.e7.

Hackl M, Andermahr J, Staat M, Bremer I, Borggrefe J, Prescher A, Müller LP, Wegmann K (2017). Suture button reconstruction of the central band of the interosseous membrane in Essex-Lopresti lesions: a comparative biomechanical investigation. J Hand Surg Eur Vol 42(4):370-376.

Hackl M, Wegmann K, Kahmann SL, Heinze N, Staat M, Neiss WF, Scaal M, Müller LP (2017). Radial shortening osteotomy reduces radiocapitellar contact pressures while preserving valgus stability of the elbow. Knee Surg Sports Traumatol Arthrosc 25(7):2280-2288.

Hackl M, Wegmann K, Koslowsky TC, Zeifang F, Schoierer O, Müller LP (2017). Rare implant-specific complications of the MoPyC radial head prosthesis. J Shoulder Elbow Surg 26(5):830-837.

Hackl M, Wegmann K, Ries C, Lappen S, Scaal M, Müller LP (2017). Annular ligament reconstruction with the superficial head of the brachialis: surgical technique and biomechanical evaluation. Surg Radiol Anat 39(6):585-591.

Kamper M, Paulsson M, Zaucke F (2017). Absence of collagen IX accelerates hypertrophic differentiation in the embryonic mouse spine through a disturbance of the Ihh-PTHrP feedback loop. Cell Tissue Res 367(2):359-367.

Leschinger T, Hackl M, Zeifang F, Scaal M, Müller LP, Wegmann K (2017). Nerve supply of the subscapularis during anterior shoulder surgery: definition of a potential risk area. Arch Orthop Trauma Surg 137(1):135-140.

Leschinger T, Müller LP, Hackl M, Scaal M, Schmidt-Horlohé K, Wegmann K (2017). Concomitant injury of the annular ligament in fractures of the coronoid process and the supinator crest. J Shoulder Elbow Surg 26(4):604-610.

Zheng W, Rogoschin J, Niehoff A, Oden K, Kulling SE, Xie M, Diel P (2017). Combinatory effects of phytoestrogens and exercise on body fat mass and lipid metabolism in ovariectomized female rats. J Steroid Biochem Mol Biol [Epub ahead of print].



Belavý DL, Albracht K, Bruggemann GP, Vergroesen PA, van Dieën JH (2016). Can exercise positively influence the intervertebral disc? Sports Med 46(4):473-85.

Dargel J, Pennig L, Schnurr C, Boese CK, Eysel P, Oppermann J (2016). [Should we use hip-ankle radiographs to assess the coronal alignment after total knee arthroplasty?]. Orthopade 45(7):591-6.

Dargel J, Pennig L, Schnurr C, Boese CK, Eysel P, Oppermann J (2016). Erratum to: Should we use hip-ankle radiographs to assess the coronal alignment after total knee arthroplasty?] Orthopade 45(8):700.

Hackl M, Bercher M, Wegmann K, Müller LP, Dargel J (2016). Functional anatomy of the lateral collateral ligament of the elbow. Arch Orthop Trauma Surg 136(7):1031-7.

Hackl M, Heinze N, Wegmann K, Lappen S, Leschinger T, Burkhart KJ, Scaal M, Müller LP (2016).The circumferential graft technique for treatment of multidirectional elbow instability: a comparative biomechanical evaluation. J Shoulder Elbow Surg 25(1):127-35.

Hackl M, Lappen S, Neiss WF, Scaal M, Müller LP, Wegmann K (2016). [The bare area of the proximal ulna: An anatomical study on optimizing olecranon osteotomy]. Orthopade 45(10):887-94.

Hackl M, Leschinger T, Müller LP, Wegmann K (2016). [Chronic ligamentous instability of the elbow] Orthopade 45(10):809-21.

Hackl M, Leschinger T, Ries C, Neiss WF, Müller LP, Wegmann K (2016). [Lateral ulnar collateral ligament reconstruction: A biomechanical analysis of posterolateral rotatory instability of the elbow]. Orthopade 45(10):895-900.

Heilig J, Paulsson M, Zaucke F (2016). Insulin-like growth factor 1 receptor (IGF1R) signaling regulates osterix expression and cartilage matrix mineralization during endochondral ossification. Bone 83:48-57.

Hoyer-Kuhn H, Franklin J, Allo G, Kron M, Netzer C, Eysel P, Hero B, Schoenau E, Semler O (2016). Safety and efficacy of denosumab in children with osteogenesis imperfecta - a first prospective trial. J Musculoskelet Neuronal Interact 16(1):24-32.

Kamper M, Hamann N, Prein C, Clausen-Schaumann H, Farkas Z, Aszodi A, Niehoff A, Paulsson M, Zaucke F (2016). Early changes in morphology, bone mineral density and matrix composition of vertebrae lead to disc degeneration in aged collagen IX -/- mice. Matrix Biol 49:132-43.

Leschinger T, Müller LP, Hackl M, Scaal M, Schmidt-Horlohé K, Wegmann K (2016). Concomitant injury of the annular ligament in fractures of the coronoid process and the supinator crest. J Shoulder Elbow Surg. pii: S1058-2746(16)30450-5.

Leschinger T, Müller LP, Hackl M, Wegmann K (2016). The cortical irregularity in the transition zone of the radial head and neck: a reliable radiographic sign of an occult radial head fracture. Arch Orthop Trauma Surg 136(8):1115-20.

Müller DR, Basso F, Kurrat A, Soukup ST, Niehoff A, Kulling SE, Diel P (2016). Dose-dependent effects of isoflavone exposure during early lifetime on development and androgen sensitivity in male Wistar rats. Mol Nutr Food Res 60(2):325-36.

Oswald I, Rickert M, Brüggemann GP, Niehoff A, Fonseca Ulloa CA, Jahnke A (2017). The influence of cryopreservation and quick-freezing on the mechanical properties of tendons. J Biomech 64:226-230.

Park J, Yu YP, Zhou CY, Li KW, Wang D, Chang E, Kim DS, Vo B, Zhang X, Gong N, Sharp K, Steward O, Vitko I, Perez-Reyes E, Eroglu C, Barres B, Zaucke F, Feng G, Luo ZD (2016). Central mechanisms mediating thrombospondin-4 induced pain states. J Biol Chem 291(25):13335-48.

Schulz JN, Nüchel J, Niehoff A, Bloch W, Schönborn K, Hayashi S, Kamper M, Brinckmann J, Plomann M, Paulsson M, Krieg T, Zaucke F, Eckes B (2016). COMP-assisted collagen secretion - a novel intracellular function required for fibrosis. J Cell Sci 129(4):706-16.

Spies CK, Niehoff A, Unglaub F, Müller LP, Langer MF, Neiss WF, Oppermann J (2016). Biomechanical comparison of transosseous re-fixation of the deep fibres of the distal radioulnar ligaments versus deep and superficial fibres: a cadaver study. Int Orthop 40(2):315-21.

Wegmann K, Zhang W, Strauss V, Ries C, Müller LP, Burkhart KJ (2016). Is the distal radioulnar variance useful for identification of radial head prosthesis overlengthening? A cadaver study. Eur J Med Res 21(1):12.

Zigrino P, Brinckmann J, Niehoff A, Lu Y, Giebeler N, Eckes B, Kadler KE, Mauch C (2016). Fibroblast-derived MMP-14 regulates collagen homeostasis in adult skin. J Invest Dermatol 136(8):1575-83.

Book chapter

Liphardt AM, Brüggemann GP, Niehoff A (2016). Adaptation of cartilage to immobilization. In: Schneider S (eds.). Exercise in Space. Springer Briefs in Space Life Sciences. Springer Verlag, Heidelberg, Germany: p. 15-38.



Bleuel J, Zaucke F, Brüggemann GP, Heilig J, Wolter ML, Hamann N, Firner S, Niehoff A (2015). Moderate cyclic tensile strain alters the assembly of cartilage extracellular matrix proteins in vitro. J Biomech Eng 137(6):061009.

Bleuel J, Zaucke F, Brüggemann GP, Niehoff A (2015). Effects of cyclic tensile strain on chondrocyte metabolism: a systematic review. PLoS One 10(3):e0119816.

Hackl M, Damerow D, Leschinger T, Scaal M, Müller LP, Wegmann K (2015). Radial nerve location at the posterior aspect of the humerus: an anatomic study of 100 specimens. Arch Orthop Trauma Surg 135(11):1527-32.

Hackl M, Lappen S, Burkhart KJ, Leschinger T, Scaal M, Müller LP, Wegmann K (2015). Elbow positioning and joint insufflation substantially influence median and radial nerve locations. Clin Orthop Relat Res 473(11):3627-34.

Hackl M, Wegmann K, Taibah S, Burkhart KJ, Scaal M, Müller LP (2015). Peri-implant failure in dual plating of the distal humerus-A biomechanical analysis with regard to screw and plate positioning. Injury 46(1):2142-5.

Heppner JM, Zaucke F, Clarke LA (2015). Extracellular matrix disruption is an early event in the pathogenesis of skeletal disease in mucopolysaccharidosis I. Mol Genet Metab 114(2):146-55.

Knipper JA, Willenborg S, Brinckmann J, Bloch W, Maaß T, Wagener R, Krieg T, Sutherland T, Munitz A, Rothenberg ME, Niehoff A, Richardson R, Hammerschmidt M, Allen JE, Eming SA (2015). Interleukin-4 receptor α signaling in myeloid cells controls collagen fibril assembly in skin repair. Immunity 43(4):803-16.

Schulz JN, Zeltz C, Sørensen IW, Barczyk M, Carracedo S, Hallinger R, Niehoff A, Eckes B, Gullberg D (2015). Reduced granulation tissue and wound strength in the absence of α11β1 integrin. J Invest Dermatol 135(5):1435-44.

Stark C, Hoyer-Kuhn HK, Semler O, Hoebing L, Duran I, Cremer R, Schoenau E (2015). Neuromuscular training based on whole body vibration in children with spina bifida: a retrospective analysis of a new physiotherapy treatment program. Childs Nerv Syst 31(2): 301-9.

Wegmann K, Lamsfuss J, Ries C, Neiss WF, Franklin J, Müller LP, Burkhart KJ (2015). Identification of overlengthening after replacement of the radial head with a bipolar prosthesis. Arch Orthop Trauma Surg 135(12):1669-74.

Xin W, Heilig J, Paulsson M, Zaucke F (2015). Collagen II regulates integrin expression profile and chondrocyte differentiation. Connect Tissue Res 56(4):307-14.

Zwolanek D, Flicker M, Kirstätter E, Zaucke F, van Osch GJ, Erben RG (2015). β1 integrins mediate attachment of mesenchymal stem cells to cartilage lesions. Biores Open Access 4(1):39-53.



Ganse B, Yang PF, Brüggemann GP, Müller LP, Rittweger J, Koy T (2014). In vivo measurements of human bone deformation using optical segment tracking: surgical approach and validation in a three-point bending test. J Musculoskelet Neuronal Interact 14(1):95-103.

Hamann N, Brüggemann GP, Niehoff A (2014). Topographical variations in articular cartilage and subchondral bone of the normal rat knee are age-related. Ann Anat 196(5):278-85.

Hoyer-Kuhn H, Semler O, Schoenau E (2014). Effect of denosumab on the growing skeleton in osteogenesis imperfecta. J Clin Endocrinol Metab 99:3954-5.

Hoyer-Kuhn HK, Semler O, Stark C, Struebing N, Goebel O, Schoenau E (2014). A specialized rehabilitation approach improves mobility in children with osteogenesis imperfecta. J Musculoskelet Neuronal Interact 14(4):445-53.

Karamanidis K, Oberländer KD, Niehoff A, Epro G, Brüggemann GP (2014). Effect of exercise-induced enhancement of the leg-extensor muscle-tendon unit capacities on ambulatory mechanics and knee osteoarthritis markers in the elderly. PLoS One 9(6):e99330.

Knoop K, Hoyer-Kuhn H, Schoenau E, Semler O (2014). Sinn und Nutzen der Knochendichtemessung in der Pädiatrie. Pädiat Prax 83:111-20.

Koy T, Zange J, Rittweger J, Pohle-Fröhlich R, Hackenbroch M, Eysel P, Ganse B (2014). Assessment of lumabr intervertebral disc glycosaminoglycan content by gadolinium-enhanced MRI before and after 21-days of head-down-tilt bedrest. PLoS One 9(11):e112104.

Lettmann S, Bloch W, Maaß T, Niehoff A, Schulz JN, Eckes B, Eming SA, Bonaldo P, Paulsson M, Wagener R (2014). Col6a1 null mice as a model to study skin phenotypes in patients with collagen VI related myopathies: expression of classical and novel collagen VI variants during wound healing. PLoS One 9(8):e105686.

Niehoff A, Lechner P, Ratiu O, Reuter S, Hamann N, Brüggemann GP, Schönau E, Bloch W, Beccard R (2014). Effect of whole-body vibration and insulin-like growth factor-I on muscle paralysis-induced bone degeneration after botulinum toxin injection in mice. Calcif Tissue Int 94(4):373-83.

Ruthard J, Kamper M, Renno JH, Kühn G, Hillebrand U, Höllriegl S, Johannis W, Zaucke F, Klatt A (2014). COMP does not directly modify the expression of genes involved in cartilage homeostasis in contrast to several other cartilage matrix proteins. Connect Tissue Res 55(5-6):348-56.

Stark C, Hoyer-Kuhn H, Knoop K, Schoenau H, Schoenau E, Semler O (2014). [Secondary forms of osteoporosis. Special features of diagnostics in childhood and adolescence]. [Article in German]. Z Rheumatol 73(4):335-41.